Our Platform

The Untapped Opportunity of Immunometabolism:
The Key to Unlocking Autoimmunity

Rheos uses a systems-level approach to develop a comprehensive understanding of metabolic reprogramming, which allows us to define a novel understanding of disease.

Our Platform – Target ID

The foundation of our product engine is the bioinformatic integration of multi-omic datasets to create immunometabolism network maps (imMAPS™) that elucidate both high-value targets and associated metabolite biomarkers to accelerate drug discovery and development.

imMAPs™ – defining shifts in metabolism

The function of immune cells is regulated by a network of intracellular metabolic programming, or immunometabolism. Mapping this network allows Rheos to understand the critical pathways that regulate the activation or suppression of immune cells in diseases, and identify the key therapeutic nodes for reprogramming the metabolism of immune cells.

Unravelling the complexities of autoimmunity

We have implemented a first-in-field approach that builds a comprehensive, systems-level understanding of the pathways that define the heterogeneous dysregulation driving immune-mediated diseases.

This ability to define metabolic pathways enables mechanism-based subsetting of patients both within and across diseases, paving the way for true precision medicine in autoimmunity.