Careers

Senior Research Associate/Associate Scientist, Biology

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January 31, 2020

The Role

Responsible for initiating, designing and executing experiments that support scientific projects relevant to different immune related diseases. Ability to perform a variety of immune cell based in vitro assays utilizing both cellular and molecular biology techniques. Effectively communicate results and conclusions to cross-functional project teams.

 

Responsibilities 

  • Responsible for developing and carrying out in vitro immunological assays to support drug discovery.
  • Support scientists in developing new assays to advance key programs. For example: setting up of mixed lymphocyte reactions, Treg suppression assays, in vitro cytotoxicity assays
  • Partner with bioinformatics and metabolism scientists to analyze and interpret data to generate novel hypothesis and validate targets
  • Participate in drug-discovery efforts including developing novel assays for compound screening or biomarker identification

Requirements

  •  Bachelors in Cellular and Molecular Immunology, cancer biology or Biochemistry with 5-8 years OR MS with 2-5 years relevant and extensive experience in immunology research and development in the Biotech industry
  •  Hands-on experience isolating and culturing immune cells in vitro; experience with cellular phenotyping by flow cytometry is a plus
  • Expertise in genetic manipulation using technologies such as CRISPR, shRNA, lentiviral/retroviral transduction, RNAi
  • Previous experience with flow cytometry, western blotting, ELISA, qPCR, and Seahorse techniques; knowledge of relevant data analysis software such as FlowJo and Prism
  • Previous experience working with and/or knowledge of mouse models of autoimmune disease is preferred
  • Experience with CRO management is a plus
  • Prior experience or track record in Immunometabolism a huge plus
  • Strong core competencies in molecular biology, cell biology and assay development
  • Ability to design and troubleshoot experiments independently
  • Excellent written and verbal communication skills
  • Organized and detail-oriented, able to maintain accurate documentation of experiments in an electronic lab notebook
  • Collaborative, able to work effectively in a cross-functional matrixed organization
  • Innovative, creative thinker; able to apply a wide variety of scientific concepts to solve problems

Apply Now

At Rheos we endeavor to create an environment where great people have the opportunity to do great things.  We are pioneering new science and that takes creativity, innovation, integration and lots of teamwork to solve complex challenges.  We are risk takers and desire that our work at Rheos creates a new paradigm for immune-mediated diseases.

A highlight of our current benefit offerings:

  • Highly competitive healthcare coverage through Blue Cross Blue Shield, dental coverage through Delta Dental and vision coverage through VSP.
  • 401k with match
  • Discretionary time off in addition to a 2 shutdowns per year (summer and winter) and additional company holidays
  • Complementary Long- and Short-Term Disability and Life Insurance
  • Monthly Cell Phone reimbursement
  • Free parking, monthly subway pass or subsidized commuter rail pass

Rheos Medicines is proud to be an equal opportunity employer and to provide equal opportunities to all employees and applicants for employment without regard to race, color, religion, sex or gender identity, national origin, age, disability, sexual orientation or genetics. In addition to federal law requirements, Rheos Medicines complies with applicable state and local laws governing nondiscrimination in employment.

 

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