Careers

Senior RA / Associate Scientist Biology

Cambridge, MA
November 19, 2019


The Role

Responsible for initiating, designing and developing new scientific projects relevant to different immune related diseases. Ability to also perform a variety of immune based in vitro assays including both cellular and molecular biology techniques. Familiar with


Major Responsibilities

 

  • Responsible for developing in vitro immunological assays in relevant immune mediated diseases
  • Support scientists in developing new assays for example; setting up of mixed lymphocyte reactions, Treg suppression assays, in vitro cytotoxicity assays and projects
  • Independently design, execute studies and perform data analyses
  • Partner with bioinformatics and metabolism scientists to analyze and interpret data to generate novel hypothesis and validate targets for modulation of immune cell functions
  • Establish novel technologies / platforms for interrogating immune cells in human patient tissues
  • Participate in drug-discovery efforts including developing novel assays for compound screening or biomarker identification 
  • Test and implement cutting edge technologies such as Seahorse Bioflux analyses to drug new targets


Requirements

Requirements and Qualifications:

 

Education and Training:

Bachelors in Cellular and Molecular Immunology, cancer biology or Biochemistry with 5-8 years OR MS with 2-5 years’ with relevant and extensive experience in immunology research and development in the Biotech industry

 

Required Experience:

  • Experience in Immune cell biology and/or biochemistry conducting high quality science in an industry setting.
  • Experience in western blotting, ELISA, and MSD
  • Previous experience working and/or knowledge of mouse models, CRO management is a plus. 
  • Experience with data analysis including Prism and FlowJo
  • Experience working in a cross-functional matrixed organization.
  • Prior experience or track record in Immunometabolism a huge plus

Knowledge, Skills & Abilities:

  • Strong core competencies in molecular biology, cell biology and assay development
  • Proficiency in primary immune cell isolation and culture
  • Strong expertise in genetic manipulation using technologies such as CRISPR, shRNA, lentiviral/retroviral transduction, RNAi
  • Hands-on knowledge of flow cytometry and FACS analysis techniques
  • Ability to design and develop independent projects
  • Ability to be creative and apply a wide variety of scientific concepts and innovate and solve problems

 

 

Apply Now

At Rheos, the well-being of our employees and their families is important to us.  We offer comprehensive and competitive health, financial, paid time off and many other benefits designed to promote the health and financial well-being of our employees and their families.

Note to Recruitment Agencies: Please do not forward any agency resumes. Rheos Medicine is not responsible for any fees related to resumes that are unsolicited.

 

Equal Opportunity Employer M/F/D/V.

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