Scientist, Computational Biology and Bioinformatics

Cambridge, MA
March 06, 2019

The Role:

Rheos Medicines is developing a platform for drug discovery and development in the novel area of immunometabolism. We are looking for a highly motivated, collaborative and innovative computational scientist who will work at the leading edge of bioinformatics, computational biology, immunology and systems biology. This individual will play a key role in building Rheos’ computational engine to drive target discovery through analysis and integration of multi-dimensional omics datasets.

Major Responsibilities

  • Implement and apply novel bioinformatics methods on complex omics datasets; e.g. single cell technologies, epigenomics
  • Build, update and maintain computational tools, pipelines and creative visualizations
  • Identify and curate relevant large-scale public dataset
  • Participate in project teams and contribute to experimental design and data analysis, interpretation and communication of results             


Requirements and Qualifications


  • PhD in Computational Biology, Bioinformatics or a related field with 2+ years’ work experience or MS with 5+ years relevant work experience. 

Required Experience:

  • Experience in analysis of single-cell technologies
  • Experience with network biology and algorithms a plus
  • Experience with open source bioinformatics tools and pipelines
  • Hands-on experience on with data visualization tools (R-Shiny, Spotfire, etc.) and multi-dimensional dataset visualization
  • Good publication record

Knowledge, Skills & Abilities:

  • Strong programming skills in R or Python
  • Familiar with good practices for reproducible research (Github, notebooks)
  • Familiar with high performance computing (preferably cloud computing)
  • Excellent written and oral communication skills.

Preferred Qualifications:

  • Prior experience in biotech/pharma industry drug discovery 
  • Experience in computational pipelines for analysis of complex omics datasets, such as single-cell RNA-Seq, ATAC-Seq, etc.
  • Experience in integrative analysis of multi-dimensional omics data 
  • Familiarity with Amazon Web Services (AWS) or similar cloud-computing platform

Apply Now

At Rheos, the well-being of our employees and their families is important to us.  We offer comprehensive and competitive health, financial, paid time off and many other benefits designed to promote the health and financial well-being of our employees and their families.

Note to Recruitment Agencies: Please do not forward any agency resumes. Rheos Medicine is not responsible for any fees related to resumes that are unsolicited.


Equal Opportunity Employer M/F/D/V.

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