The Untapped Opportunity of Immunometabolism: A New Paradigm for Drug Discovery

The Untapped Opportunity of Immunometabolism: A New Paradigm for Drug Discovery

Immunometabolism is the intracellular metabolic programming of immune cells that dictate
their fate and function. Dysregulated immune cell metabolism can cause inflammation or overt immune suppression, leading to autoimmune diseases or cancer. Because immunological function is directly linked to metabolism, intervening in metabolic pathways has the potential to be a powerful therapeutic lever.

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In addition, modulating metabolic pathways can cause epigenetic modifications, which we believe have the potential to drive persistent changes in the functional state of immune cells.

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