Research Associate / Senior Research Associate, Biology

Position Details

Date Posted:

March 18, 2021

Location:

Cambridge, MA

Description:

The Role

The Research Associate / Senior Research Associate will develop & implement appropriate assays and systems required for the identification & validation of targets for autoimmune/inflammatory diseases, advancement of high priority projects, as well as the company‚Äôs product engine.  

Responsibilities

  • Development and implementation of a diverse set of cellular/molecular immunology assays and systems
  • Design and execution of experiments used to identify and validate potential drug targets for autoimmune and inflammatory diseases
  • Participation in planning and troubleshooting of experiments to support project goals
  • Partner with scientific leadership design, execute, troubleshoot, and interpret biological experiments in support of program objectives
  • Develop protocols for diverse assays
  • Maintain accurate documentation of experiments
  • Interact and communicate results and conclusions within the biology group and cross functional project teams
  • Review the scientific literature, attend user groups, to remain abreast of developments in relevant fields

Requirements:

  • BS or MS in immunology, cell and/or molecular biology, or pharmacology
  • Minimum of 2-5 years of hands on experience in cellular and molecular immunology techniques such as flow cytometry, Western blots, ELISA, qPCR 
  • Experience in purification and/or culturing of immune cells such as lymphocytes, monocytes, macrophages, neutrophils; experience with primary human cells a plus
  • Experience with the ability to assess target biology with genetic perturbation techniques such as CRISPR-Cas9, shRNA, lentiviral/retroviral transduction, RNAi
  • Experience with data logging in electronic notebooks as well as the use of visualization software and associated analysis of rich cellular datasets.
  • Effective Communication of results and conclusions 
  • Demonstrated ability to thrive in a team environment
  • Ability to function equally well in self-starter mode, as well as, a member of a matrixed team
  • Strong experimental background and a rigorous, analytical approach to problem solving
  • Experience in working with other cell types such as synovial fibroblasts, dermal fibroblasts, keratinocytes, DCs