Research Associate / Senior Research Associate, Biology

Position Details

Date Posted:

September 23, 2020

Location:

Cambridge, MA

Description:

The Role

The Research Associate / Senior Research Associate will develop & implement appropriate assays and systems required for the identification & validation of targets for autoimmune/inflammatory diseases, advancement of high priority projects, as well as, the company’s product engine.

Responsibilities

  • Development and implementation of a diverse set of cellular/molecular immunology, biochemical and metabolic assays
  • Design and execution of experiments used to identify and validate potential drug targets for autoimmune and inflammatory diseases
  • Effective Communication of results and conclusions
  • Participation in planning and troubleshooting of experiments to support project goals

Requirements:

  • BS or MS in immunology, cell and/or molecular biology, or pharmacology
  • Minimum of 2-5 years of hands on experience in cellular and molecular immunology techniques such as flow cytometry, immunoblotting, ELISA, qPCR (nice to have)
  • Experience in purification and culturing of immune cells such as lymphocytes, monocytes/macrophages
  • Experience with data logging in electronic notebooks as well as the use of visualization software and associated analysis of rich cellular datasets.
  • Demonstrated ability to thrive in a team environment
  • Strong experimental background and a rigorous, analytical approach to problem solving

Nice to haves

  • Experience in working with other cell types such as synovial fibroblasts, dermal fibroblasts, keratinocytes, DCs
  • Target validation experience with the ability to assess target biology with genetic perturbation techniques such as CRISPR-Cas9 
  • 3 to 5 years of hands-on drug discovery experience
  • In partnership with scientific leadership have experienced design, execution, troubleshooting, and interpretation of biological experiments in support of program objectives
  • Develop protocols for diverse assays
  • Maintain accurate documentation of experiments
  • Interact and communicate results and conclusions within the biology group and cross functional project teams
  • Review the scientific literature, attend user groups, to remain abreast of developments in relevant fields
  • Ability to function equally well in self-starter mode, as well as, a member of a matrixed team